The mediterranean diet and young people

The Multicenter Study on the diet habits of young people

The National Italian Research Council, Institute of Neuroscience, Aging Branch, Padova coordinated a research project on the dietary habits of young people and obesity. The research was conducted by the University of Padova and sponsored by the Italian Ministry of Agriculture in collaboration with the Friends of Ostuni Association and the towns of Ostuni, Conegliano (Treviso) and Montichiari (Brescia). By clicking on this link you can read the article outlining the study’s results that was published in the Nutrition Research journal.

Scientific References

Here below is a selection of articles on studies examining the effects of the Mediterranean diet on human health. It is a list of the latest, most important scientific publications regarding the Mediterranean diet:

  • St Leger AS, Cochrane AL, Moore F. Ischaemic heart-disease and wine. Lancet 1979; 1(8129):1294
  • JL Richard, “Les facteurs de risque coronarien: Le paradoxe français,” Archives des Maladies du Coeur et des Vaisseaux 80 (April 1987): 17–21
  • Milatovich L. – Mondelli G. La tecnologia della pasta alimentare, Chirotti Editori. Pinerolo 1990; p:331
  • Keys A. Mediterranean diet and public health: personal reflections. Am J Clin Nutr 1995; 61(6 Suppl):1321S-1323S
  • Lucisano M, Pagani MA. Cereali e derivati. In Daghetta A. Gli alimenti. Aspetti tecnologici e nutrizionali. Collana ITEMS, Milano 1997; p: 7-68
  • Solfrizzi V, Panza F, Torres F, Mastroianni F, Del Parigi A, Venezia A, Capurso A. High monounsaturated fatty acids intake protects against age-related cognitive decline. Neurology 1999; 52(8):1563-1569
  • Carluccio MA, Massaro M, Bonfrate C, Siculella L, Maffia M, Nicolardi G, Distante A, Storelli C, De CaterinaR. Oleic acid inhibits endothelial activation: A direct vascular antiatherogenic mechanism of a nutritional component in the mediterranean diet. Arterioscler Thromb Vasc Biol 1999; 19(2):220-228
  • de Lorgeril M, Salen P, Martin JL, Monjaud I, Delaye J, Mamelle N. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation 1999 99(6):779-785
  • Rimm EB, Williams P, Fosher K, Criqui M, Stampfer MJ. Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors. BMJ 1999; 319(7224):1523-1528
  • Executive Summary of the Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497
  • Kris-Etherton P, Eckel RH, Howard BV, St Jeor S, Bazzarre TL. AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease. Circulation 2001;103:1823-1825
  • Hu, F.B. and W.C. Willett, Optimal diets for prevention of coronary heart disease. JAMA 2002; 288(20):2569-2578
  • Hu F.B. The Mediterranean diet and mortality–olive oil and beyond. N Engl J Med. 2003;348(26):2595-2596.
  • Singh, R.B., G. Dubnov, M.A. Niaz, S. Ghosh, R. Singh, S.S. Rastogi, O. Manor, D. Pella, and E.M. Berry, Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial. Lancet, 2002; 360(9344) 1455-1461
  • Linee guida per una sana e corretta alimentazione italiana. Istituto Nazionale di Ricerca per gli Alimenti e la Nutrizione. Revisione 2003
  • Trichopoulou, A., T. Costacou, C. Bamia, and D. Trichopoulos, Adherence to a Mediterranean diet and survival in a Greek population. N Engl J Med, 2003; 348(26):2599-2608.
  • Pitsavos C, Panagiotakos DB, Chrysohoou C, Stefanadis C. Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study. BMC Public Health 2003; 3:32
  • Chrysohoou C, Panagiotakos DB, Pitsavos C, Das UN, Stefanadis C. Adherence to the Mediterranean diet attenuates inflammation and coagulation process in healthy adults: The ATTICA Study. J Am Coll Cardiol 2004; 44(1):152-158
  • Yusuf S, Hawken S, Ounpuu S, Dans T, Avezum A, Lanas F, McQueen M, Budaj A, Pais P, Varigos J, Lisheng L; INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004; 364(9438):937-952
  • Knoops KT, de Groot LC, Kromhout D, Perrin AE, Moreiras-Varela O, Menotti A, van Staveren WA. Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA 2004; 292(12):1433-1439
  • Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, Gordon DJ, Krauss RM, Savage PJ, Smith SC Jr, Spertus JA, Costa F: Diagnosis and management of the metabolic syndrome: an American Heart Association National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112:2735-2752
  • Beauchamp GK, Keast RS, Morel D, Lin J, Pika J, Han Q, Lee CH, Smith AB, Breslin PA. Phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature2005; 437(7055):45-46
  • Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006; 5(6):493-506
  • Estruch R, Martínez-González MA, Corella D, Salas-Salvadó J, Ruiz-Gutiérrez V, Covas MI, Fiol M, Gómez-Gracia E, López-Sabater MC, Vinyoles E, Arós F, Conde M, Lahoz C, Lapetra J, Sáez G, Ros E; PREDIMED Study Investigators. Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann Intern Med 2006; 145(1):1-11
  • Seguí-Gómez M, de la Fuente C, Vázquez Z, de Irala J, Martínez-González MA. Cohort profile: the ‘Seguimiento Universidad de Navarra’ (SUN) study. Int J Epidemiol 2006; 35(6):1417-1422
  • Martínez-González MA. The SUN cohort study (Seguimiento University of Navarra). Public Health Nutr 2006; 9(1A):127-131
  • Martínez-González MA, de la Fuente-Arrillaga C, Nunez-Cordoba JM, Basterra-Gortari FJ, Beunza JJ, Vazquez Z, Benito S, Tortosa A, Bes-Rastrollo M. Adherence to Mediterranean diet and risk of developing diabetes: prospective cohort study. BMJ 2008; 336(7657):1348 -1351
  • Benetou V, Trichopoulou A, Orfanos P, Naska A, Lagiou P, Boffetta P, Trichopoulos D; Greek EPIC cohort. Conformity to traditional Mediterranean diet and cancer incidence: the Greek EPIC cohort. Br J Cancer 2008; 99(1):191-195
  • Sofi F, Cesari F, Abbate R, Gensini GF, Casini A. Adherence to Mediterranean diet and health status: meta-analysis. BMJ 2008;11:337-344
  • Covas MI, Konstantinidou V, Fitó M. Olive oil and cardiovascular health. J Cardiovasc Pharmacol 2009; 54(6):477-482
  • Raederstorff D. Antioxidant activity of olive polyphenols in humans: a review. Int J Vitam Nutr Res 2009;79(3):152-165